St George and Sutherland Medical Research Foundation

Dr Jose Perdomo – 2019 SSMRF Grant Recipient

The role of neutrophils in the pathology of immune thrombocytopenia

Amount Funded: $49,554.40

Project Description: This project will study a bleeding condition called immune thrombocytopenia (ITP). In ITP, clotting is compromised due to low numbers of a type of blood cell called platelets that are needed for normal blood clotting. Bleeding can occur under the skin, gums and other tissues. In some cases, patients may have internal bleeding in the intestines or, more seriously, in the brain. Platelets numbers
decrease because the immune system can malfunction, and the body produces antibodies that attack its own platelets. This study will look at the potential role that a type of white cell, called neutrophils, plays in the development of ITP. The knowledge gained in this study may contribute to better management and treatment of ITP.

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